Membrane extraction with styrene-maleic acid copolymer results in insulin receptor autophosphorylation in the absence of ligand

Extraction of integral membrane proteins with poly(styrene-co-maleic acid) provides a promising alternative to detergent extraction. A major advantage of extraction using copolymers rather than detergent is the retention of the lipid bilayer around the proteins. Here we report the first functional i...

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Detalles Bibliográficos
Autores principales: Morrison, Kerrie A., Wood, Laura, Edler, Karen J., Doutch, James, Price, Gareth J., Koumanov, Francoise, Whitley, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894449/
https://www.ncbi.nlm.nih.gov/pubmed/35241773
http://dx.doi.org/10.1038/s41598-022-07606-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894449/
https://www.ncbi.nlm.nih.gov/pubmed/35241773
http://dx.doi.org/10.1038/s41598-022-07606-5

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