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Membrane extraction with styrene-maleic acid copolymer results in insulin receptor autophosphorylation in the absence of ligand
Extraction of integral membrane proteins with poly(styrene-co-maleic acid) provides a promising alternative to detergent extraction. A major advantage of extraction using copolymers rather than detergent is the retention of the lipid bilayer around the proteins. Here we report the first functional i...
Autores principales: | Morrison, Kerrie A., Wood, Laura, Edler, Karen J., Doutch, James, Price, Gareth J., Koumanov, Francoise, Whitley, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894449/ https://www.ncbi.nlm.nih.gov/pubmed/35241773 http://dx.doi.org/10.1038/s41598-022-07606-5 |
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