TRIM45 causes neuronal damage by aggravating microglia-mediated neuroinflammation upon cerebral ischemia and reperfusion injury

Excessive and unresolved neuroinflammation is a key component of the pathological cascade in brain injuries such as ischemic stroke. Tripartite motif-containing 45 (TRIM45) is a ubiquitin E3 ligase involved in various critical biological processes. However, the role of TRIM45 in cerebral ischemia re...

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Detalles Bibliográficos
Autores principales: Xia, Qian, Zhan, Gaofeng, Mao, Meng, Zhao, Yin, Li, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894463/
https://www.ncbi.nlm.nih.gov/pubmed/35217833
http://dx.doi.org/10.1038/s12276-022-00734-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894463/
https://www.ncbi.nlm.nih.gov/pubmed/35217833
http://dx.doi.org/10.1038/s12276-022-00734-y

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