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Intestinal AMPK modulation of microbiota mediates crosstalk with brown fat to control thermogenesis

The energy-dissipating capacity of brown adipose tissue through thermogenesis can be targeted to improve energy balance. Mammalian 5′-AMP-activated protein kinase, a key nutrient sensor for maintaining cellular energy status, is a known therapeutic target in Type II diabetes. Despite its well-establ...

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Detalles Bibliográficos
Autores principales: Zhang, Eryun, Jin, Lihua, Wang, Yangmeng, Tu, Jui, Zheng, Ruirong, Ding, Lili, Fang, Zhipeng, Fan, Mingjie, Al-Abdullah, Ismail, Natarajan, Rama, Ma, Ke, Wang, Zhengtao, Riggs, Arthur D., Shuck, Sarah C., Yang, Li, Huang, Wendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894485/
https://www.ncbi.nlm.nih.gov/pubmed/35241650
http://dx.doi.org/10.1038/s41467-022-28743-5