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ZNF191 alters DNA methylation and activates the PI3K‐AKT pathway in hepatoma cells via transcriptional regulation of DNMT1

BACKGROUND: Alteration of DNA methylation is an important event in pathogenesis and progression of hepatocellular carcinoma (HCC). DNA methyltransferase (DNMT) 1, the foremost contributor in DNA methylation machinery, was revealed elevated in HCC and significantly correlates with poor prognosis. How...

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Detalles Bibliográficos
Autores principales: Liu, Yufeng, Cheng, Hanghang, Cheng, Chenchen, Zheng, Fengyun, Zhao, Zhonghua, Chen, Qi, Zeng, Wenjiao, Zhang, Pingzhao, Huang, Cheng, Jiang, Wei, Liu, Xiuping, Liu, Guoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894703/
https://www.ncbi.nlm.nih.gov/pubmed/35092191
http://dx.doi.org/10.1002/cam4.4535