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Deciphering Cell-Type-Specific Gene Expression Signatures of Cardiac Diseases Through Reconstruction of Bulk Transcriptomes

Cardiac diseases compose a fatal disease category worldwide. Over the past decade, high-throughput transcriptome sequencing of bulk heart tissues has widened our understanding of the onset and progression of cardiac diseases. The recent rise of single-cell RNA sequencing (scRNA-seq) technology furth...

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Detalles Bibliográficos
Autores principales: Wu, Xiaobin, Zhao, Xingyu, Xiong, Yufei, Zheng, Ming, Zhong, Chao, Zhou, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894713/
https://www.ncbi.nlm.nih.gov/pubmed/35252172
http://dx.doi.org/10.3389/fcell.2022.792774