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Ciclopirox Olamine Exerts Tumor-Suppressor Effects via Topoisomerase II Alpha in Lung Adenocarcinoma

BACKGROUND: Globally, lung cancer is one of the most malignant tumors, of which lung adenocarcinoma (LUAD) is the most common subtype, with a particularly poor prognosis. Ciclopirox olamine (CPX) is an antifungal drug and was recently identified as a potential antitumor agent. However, how CPX and i...

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Detalles Bibliográficos
Autores principales: Yin, Jie, Che, Gang, Jiang, Kan, Zhou, Ziyang, Wu, Lingyun, Xu, Mengyou, Liu, Jian, Yan, Senxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894728/
https://www.ncbi.nlm.nih.gov/pubmed/35251970
http://dx.doi.org/10.3389/fonc.2022.791916