Task-driven knowledge graph filtering improves prioritizing drugs for repurposing

BACKGROUND: Drug repurposing aims at finding new targets for already developed drugs. It becomes more relevant as the cost of discovering new drugs steadily increases. To find new potential targets for a drug, an abundance of methods and existing biomedical knowledge from different domains can be le...

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Detalles Bibliográficos
Autores principales: Ratajczak, Florin, Joblin, Mitchell, Ringsquandl, Martin, Hildebrandt, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894843/
https://www.ncbi.nlm.nih.gov/pubmed/35246025
http://dx.doi.org/10.1186/s12859-022-04608-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894843/
https://www.ncbi.nlm.nih.gov/pubmed/35246025
http://dx.doi.org/10.1186/s12859-022-04608-y

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