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Oocyte activation deficiency and assisted oocyte activation: mechanisms, obstacles and prospects for clinical application

BACKGROUND: Oocyte activation deficiency (OAD) is attributed to the majority of cases underlying failure of ICSI cycles, the standard treatment for male factor infertility. Oocyte activation encompasses a series of concerted events, triggered by sperm-specific phospholipase C zeta (PLCζ), which elic...

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Detalles Bibliográficos
Autores principales: Kashir, Junaid, Ganesh, Durga, Jones, Celine, Coward, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894871/
https://www.ncbi.nlm.nih.gov/pubmed/35261925
http://dx.doi.org/10.1093/hropen/hoac003