Fumaric acid ester-induced renal Fanconi syndrome: evidence of mitochondrial toxicity

BACKGROUND: Fumaric acid esters (FAEs) are used to treat chronic plaque psoriasis. Fumarate is a crucial component of the Krebs cycle and mitochondrial function. Proximal tubule cells have high energy demands and rely on aerobic respiration. Proximal tubular dysfunction can cause renal Fanconi syndr...

Descripción completa

Detalles Bibliográficos
Autores principales: Wan, Elizabeth R, Siew, Keith, Heptinstall, Lauren, Walsh, Stephen B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894934/
https://www.ncbi.nlm.nih.gov/pubmed/35261762
http://dx.doi.org/10.1093/ckj/sfaa270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894934/
https://www.ncbi.nlm.nih.gov/pubmed/35261762
http://dx.doi.org/10.1093/ckj/sfaa270

Ejemplares similares