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Fumaric acid ester-induced renal Fanconi syndrome: evidence of mitochondrial toxicity
BACKGROUND: Fumaric acid esters (FAEs) are used to treat chronic plaque psoriasis. Fumarate is a crucial component of the Krebs cycle and mitochondrial function. Proximal tubule cells have high energy demands and rely on aerobic respiration. Proximal tubular dysfunction can cause renal Fanconi syndr...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894934/ https://www.ncbi.nlm.nih.gov/pubmed/35261762 http://dx.doi.org/10.1093/ckj/sfaa270 |