Integrin Beta 4E Promotes Endothelial Phenotypic Changes and Attenuates Lung Endothelial Cell Inflammatory Responses

We previously reported integrin beta 4 (ITGB4) is an important mediator of lung vascular protection by simvastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A-reductase inhibitor. In this study, we report increased endothelial cell (EC) expression specifically of ITGB4E, an ITGB4 mRNA splice variant, b...

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Detalles Bibliográficos
Autores principales: Chen, Weiguo, Gard, Jamie M. C., Epshtein, Yulia, Camp, Sara M., Garcia, Joe G. N., Jacobson, Jeffrey R., Cress, Anne E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895044/
https://www.ncbi.nlm.nih.gov/pubmed/35250607
http://dx.doi.org/10.3389/fphys.2022.769325

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895044/
https://www.ncbi.nlm.nih.gov/pubmed/35250607
http://dx.doi.org/10.3389/fphys.2022.769325

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