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PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS‐STING‐Mediated Interferon Response

The Plk1‐interacting checkpoint helicase (PICH) protein localizes to ultrafine anaphase DNA bridges in mitosis along with a complex of DNA repair proteins. Previous studies show PICH deficiency‐induced embryonic lethality in mice. However, the function of PICH that is required to suppress embryonic...

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Detalles Bibliográficos
Autores principales: Geng, Xinwei, Zhang, Chao, Li, Miao, Wang, Jiaqi, Ji, Fang, Feng, Hanrong, Xing, Meichun, Li, Fei, Zhang, Lingling, Li, Wen, Chen, Zhihua, Hickson, Ian D., Shen, Huahao, Ying, Songmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895048/
https://www.ncbi.nlm.nih.gov/pubmed/35037428
http://dx.doi.org/10.1002/advs.202103837