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Nano‐enabled Tumor Systematic Energy Exhaustion via Zinc (II) Interference Mediated Glycolysis Inhibition and Specific GLUT1 Depletion

Despite the promise of tumor starvation therapies, they are often associated with nonspecific and incomplete energy blockade. Here, a novel paradigm of starvation therapy is proposed to synergize the “Zn(2+) interference”‐mediated glycolysis inhibition and Zn(2+)‐activating GLUT1 (Glucose transporte...

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Detalles Bibliográficos
Autores principales: Wu, Sixuan, Zhang, Kaixiang, Liang, Yan, Wei, Yongbin, An, Jingyi, Wang, Yifei, Yang, Jiali, Zhang, Hongling, Zhang, Zhenzhong, Liu, Junjie, Shi, Jinjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895132/
https://www.ncbi.nlm.nih.gov/pubmed/34913610
http://dx.doi.org/10.1002/advs.202103534