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Targeting PI3Kγ/AKT Pathway Remodels LC3‐Associated Phagocytosis Induced Immunosuppression After Radiofrequency Ablation

Residual tumors after insufficient radiofrequency ablation (IRFA) shows accelerated progression and anti‐PD‐1 resistance. It is also reported that macrophages infiltrating into residual tumors leads to anti‐PD‐1 resistance. Elements of autophagy have been detected to conjugate LC3 to be increasingly...

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Detalles Bibliográficos
Autores principales: Liu, Xiaodi, Zhang, Wenyue, Xu, Yanni, Xu, Xiaolin, Jiang, Qiongchao, Ruan, Jingliang, Wu, Ye, Zhou, Yingshi, Saw, Phei Er, Luo, Baoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895133/
https://www.ncbi.nlm.nih.gov/pubmed/35037422
http://dx.doi.org/10.1002/advs.202102182