Targeting the RT loop of Src SH3 in Platelets Prevents Thrombosis without Compromising Hemostasis

Conventional antiplatelet agents indiscriminately inhibit both thrombosis and hemostasis, and the increased bleeding risk thus hampers their use at more aggressive dosages to achieve adequate effect. Blocking integrin αIIbβ3 outside‐in signaling by separating the β3/Src interaction, yet to be proven...

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Detalles Bibliográficos
Autores principales: Mao, Jianhua, Zhu, Kongkai, Long, Zhangbiao, Zhang, Huimin, Xiao, Bing, Xi, Wenda, Wang, Yun, Huang, Jiansong, Liu, Jingqiu, Shi, Xiaofeng, Jiang, Hao, Lu, Tian, Wen, Yi, Zhang, Naixia, Meng, Qian, Zhou, Hu, Ruan, Zheng, Wang, Jin, Luo, Cheng, Xi, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895158/
https://www.ncbi.nlm.nih.gov/pubmed/35023301
http://dx.doi.org/10.1002/advs.202103228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895158/
https://www.ncbi.nlm.nih.gov/pubmed/35023301
http://dx.doi.org/10.1002/advs.202103228

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