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USP22‐mediated deubiquitination of PTEN inhibits pancreatic cancer progression by inducing p21 expression

Phosphatase and tensin homolog deleted on chromosome ten (PTEN) is a dual lipid and protein phosphatase. Multiple mechanisms contributing to the regulation of PTEN levels have been identified thus far, including post‐translational modifications, epigenetic mechanisms, and transcriptional mechanisms....

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Detalles Bibliográficos
Autores principales: Ren, Dianyun, Sun, Yan, Li, Dan, Wu, Heshui, Jin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895442/
https://www.ncbi.nlm.nih.gov/pubmed/34743406
http://dx.doi.org/10.1002/1878-0261.13137