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Targeting KRAS mutant lung cancer: light at the end of the tunnel

For decades, KRAS mutant lung adenocarcinomas (LUAD) have been refractory to therapeutic strategies based on personalized medicine owing to the complexity of designing inhibitors to selectively target KRAS and downstream targets with acceptable toxicities. The recent development of selective KRAS(G1...

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Detalles Bibliográficos
Autores principales: Drosten, Matthias, Barbacid, Mariano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895444/
https://www.ncbi.nlm.nih.gov/pubmed/34951114
http://dx.doi.org/10.1002/1878-0261.13168