4-Acetylantroquinonol B enhances cell death and inhibits autophagy by downregulating the PI3K/Akt/MDR1 pathway in gemcitabine-resistant pancreatic cancer cells

Gemcitabine (GEM) is a typical chemotherapeutic drug used to treat pancreatic cancer, but GEM resistance develops within weeks after chemotherapy. Hence, the development of a new strategy to overcome drug resistance is urgent. 4-Acetylantroquinonol B (4-AAQB), a ubiquinone derived from Taiwanofungus...

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Detalles Bibliográficos
Autores principales: Chen, Ying-Yin, Chen, Sheng-Yi, Li, Tsung-Ju, Lin, Ting-Wei, Chen, Chin-Chu, Yen, Gow-Chin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895450/
https://www.ncbi.nlm.nih.gov/pubmed/35251348
http://dx.doi.org/10.3892/ol.2022.13248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895450/
https://www.ncbi.nlm.nih.gov/pubmed/35251348
http://dx.doi.org/10.3892/ol.2022.13248

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