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RASSF1A independence and early galectin‐1 upregulation in PIK3CA‐induced hepatocarcinogenesis: new therapeutic venues

Aberrant activation of the phosphoinositide 3‐kinase (PI3K)/AKT/mTOR and Ras/mitogen‐activated protein kinase (MAPK) pathways is a hallmark of hepatocarcinogenesis. In a subset of hepatocellular carcinomas (HCCs), PI3K/AKT/mTOR signaling dysregulation depends on phosphatidylinositol‐4,5‐bisphosphate...

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Detalles Bibliográficos
Autores principales: Scheiter, Alexander, Evert, Katja, Reibenspies, Lucas, Cigliano, Antonio, Annweiler, Katharina, Müller, Karolina, Pöhmerer, Laura‐Maria‐Giovanna, Xu, Hongwei, Cui, Guofei, Itzel, Timo, Materna‐Reichelt, Silvia, Coluccio, Andrea, Honarnejad, Kamran, Teufel, Andreas, Brochhausen, Christoph, Dombrowski, Frank, Chen, Xin, Evert, Matthias, Calvisi, Diego F., Utpatel, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895452/
https://www.ncbi.nlm.nih.gov/pubmed/34748271
http://dx.doi.org/10.1002/1878-0261.13135