Prevalence of BRCA1 and BRCA2 Germline Mutations in Patients of African Descent with Early-Onset and Familial Colombian Breast Cancer

BACKGROUND: Pathogenic germline mutations in the BRCA1 and BRCA2 (BRCA1/2) genes contribute to hereditary breast/ovarian cancer (OC) in White/mestizo Colombian women. As there is virtually no genetic data on breast cancer (BC) in Colombians of African descent, we conducted a comprehensive BRCA1/2 mu...

Descripción completa

Detalles Bibliográficos
Autores principales: Vargas, Elizabeth, de Deugd, Robert, Villegas, Victoria E, Gil, Fabian, Mora, Lina, Viaña, Luis Fernando, Bruges, Ricardo, Gonzalez, Alejandro, Galvis, Juan Carlos, Hamann, Ute, Torres, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Global Health and Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895486/
https://www.ncbi.nlm.nih.gov/pubmed/35641219
http://dx.doi.org/10.1093/oncolo/oyab026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895486/
https://www.ncbi.nlm.nih.gov/pubmed/35641219
http://dx.doi.org/10.1093/oncolo/oyab026

Ejemplares similares