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Increased TOX expression associates with exhausted T cells in patients with multiple myeloma

Previous studies have shown increased aberrant expression of immune checkpoint (IC) proteins, such as programmed cell death receptor-1 (PD-1) and T cell immunoglobulin mucin-domain-containing-3 (Tim-3) on T cells from patients with multiple myeloma (MM), which result in T cell exhaustion and dysfunc...

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Detalles Bibliográficos
Autores principales: Zhao, Yujie, Liao, Pengjun, Huang, Shuxin, Deng, Tairan, Tan, Jiaxiong, Huang, Youxue, Zhan, Huien, Li, Yangqiu, Chen, Shaohua, Zhong, Liye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895562/
https://www.ncbi.nlm.nih.gov/pubmed/35246241
http://dx.doi.org/10.1186/s40164-022-00267-0