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ERAP1 is a critical regulator of inflammasome-mediated proinflammatory and ER stress responses

BACKGROUND: In addition to its role in antigen presentation, recent reports establish a new role for endoplasmic reticulum aminopeptidase 1 (ERAP1) in innate immunity; however, the mechanisms underlying these functions are not fully defined. We previously confirmed that loss of ERAP1 functions resul...

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Detalles Bibliográficos
Autores principales: Blake, Maja K., O’Connell, Patrick, Pepelyayeva, Yuliya, Godbehere, Sarah, Aldhamen, Yasser A., Amalfitano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895631/
https://www.ncbi.nlm.nih.gov/pubmed/35246034
http://dx.doi.org/10.1186/s12865-022-00481-9