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Advances in the diagnosis and treatment of sickle cell disease

Sickle cell disease (SCD), which affects approximately 100,000 individuals in the USA and more than 3 million worldwide, is caused by mutations in the βb globin gene that result in sickle hemoglobin production. Sickle hemoglobin polymerization leads to red blood cell sickling, chronic hemolysis and...

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Detalles Bibliográficos
Autores principales: Brandow, A. M., Liem, R. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895633/
https://www.ncbi.nlm.nih.gov/pubmed/35241123
http://dx.doi.org/10.1186/s13045-022-01237-z