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Acceleration of the DNA methylation clock among lynch syndrome-associated mutation carriers

BACKGROUND: DNA methylation (DNAm) age metrics have been widely accepted as an epigenetic biomarker for biological aging and disease. The purpose of this study is to assess whether or not individuals carrying Lynch Syndrome-associated mutations are affected in their rate of biological aging, as meas...

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Detalles Bibliográficos
Autores principales: Cuadros, Marta, Cano, Carlos, Garcia-Rodriguez, Sonia, Martín, José Luis, Poyatos-Andujar, Antonio, Ruiz-Cabello, Francisco, Pedrinaci, Susana, Durán, Gema, Benavides, Manuel, Bautista-Ojeda, María Dolores, Pereda, Teresa, Benitez-Cantos, Maria Soledad, Medina, Pedro, Blanco, Armando, Gonzalez, Antonio, Lizardi, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895826/
https://www.ncbi.nlm.nih.gov/pubmed/35246124
http://dx.doi.org/10.1186/s12920-022-01183-2