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Mesenchymal stem cells protect against acetaminophen hepatotoxicity by secreting regenerative cytokine hepatocyte growth factor

BACKGROUND: Acetaminophen (APAP) overdose is a major cause of the morbidity of acute liver failure. The current clinically approved treatment for APAP poisoning, N-acetylcysteine (NAC), has a limited therapeutic window, and prolonged treatment with NAC delays liver regeneration. Mesenchymal stem cel...

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Detalles Bibliográficos
Autores principales: Wang, Ping, Cui, Yan, Wang, Jing, Liu, Donghua, Tian, Yue, Liu, Kai, Wang, Xue, Liu, Lin, He, Yu, Pei, Yufeng, Li, Li, Sun, Liying, Zhu, Zhijun, Chang, Dehua, Jia, Jidong, You, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895877/
https://www.ncbi.nlm.nih.gov/pubmed/35246254
http://dx.doi.org/10.1186/s13287-022-02754-x