Inhibition of CK2 mitigates Alzheimer’s tau pathology by preventing NR2B synaptic mislocalization

Alzheimer’s disease (AD) is a neurodegenerative disorder that exhibits pathological changes in both tau and synaptic function. AD patients display increases in hyperphosphorylated tau and synaptic activity. Previous studies have individually identified the role of NR2B subunit-containing NMDA recept...

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Detalles Bibliográficos
Autores principales: Marshall, Courtney A., McBride, Jennifer D., Changolkar, Lakshmi, Riddle, Dawn M., Trojanowski, John Q., Lee, Virginia M.-Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895919/
https://www.ncbi.nlm.nih.gov/pubmed/35246269
http://dx.doi.org/10.1186/s40478-022-01331-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8895919/
https://www.ncbi.nlm.nih.gov/pubmed/35246269
http://dx.doi.org/10.1186/s40478-022-01331-w

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