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Phase Ib study of durvalumab (MEDI4736) in combination with carbon-ion radiotherapy and weekly cisplatin for patients with locally advanced cervical cancer (DECISION study): study protocol for a prospective open-label single-arm study

INTRODUCTION: Concurrent chemoradiotherapy is considered the standard treatment strategy for locally advanced cervical cancer. Most recent reports indicate that patients with bulky tumours or adenocarcinoma subtypes have poorer local control. Carbon-ion radiotherapy (CIRT) with the concurrent use of...

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Detalles Bibliográficos
Autores principales: Okonogi, Noriyuki, Usui, Hirokazu, Murata, Kazutoshi, Hori, Makoto, Kurokawa, Tomoya, Fujiwara, Tadami, Fujii, Yasuhisa, Hanawa, Michiko, Kawasaki, Yohei, Hattori, Yoko, Suzuki, Kazuko, Tsuyuki, Kyoko, Wakatsuki, Masaru, Hasegawa, Sumitaka, Yamada, Shigeru, Hanaoka, Hideki, Shozu, Makio, Tsuji, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896055/
https://www.ncbi.nlm.nih.gov/pubmed/35236732
http://dx.doi.org/10.1136/bmjopen-2021-056424