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Mechanical overload decreases tenogenic differentiation compared to physiological load in bioartificial tendons

BACKGROUND: Tenocytes as specialised fibroblasts and inherent cells of tendons require mechanical load for their homeostasis. However, how mechanical overload compared to physiological load impacts on the tenogenic differentiation potential of fibroblasts is largely unknown. METHODS: Three-dimension...

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Detalles Bibliográficos
Autores principales: Pentzold, Stefan, Wildemann, Britt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896085/
https://www.ncbi.nlm.nih.gov/pubmed/35241113
http://dx.doi.org/10.1186/s13036-022-00283-y