A deterministic code for transcription factor-DNA recognition through computation of binding interfaces

The recognition code between transcription factor (TF) amino acids and DNA bases remains poorly understood. Here, the determinants of TF amino acid-DNA base binding selectivity were identified through the analysis of crystals of TF-DNA complexes. Selective, high-frequency interactions were identifie...

Descripción completa

Detalles Bibliográficos
Autores principales: Trerotola, Marco, Antolini, Laura, Beni, Laura, Guerra, Emanuela, Spadaccini, Mariano, Verzulli, Damiano, Moschella, Antonino, Alberti, Saverio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Standard Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896162/
https://www.ncbi.nlm.nih.gov/pubmed/35261972
http://dx.doi.org/10.1093/nargab/lqac008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896162/
https://www.ncbi.nlm.nih.gov/pubmed/35261972
http://dx.doi.org/10.1093/nargab/lqac008

Ejemplares similares