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Allele-specific expression reveals genes with recurrent cis-regulatory alterations in high-risk neuroblastoma
BACKGROUND: Neuroblastoma is a pediatric malignancy with a high frequency of metastatic disease at initial diagnosis. Neuroblastoma tumors have few recurrent protein-coding mutations but contain extensive somatic copy number alterations (SCNAs) suggesting that mutations that alter gene dosage are im...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896304/ https://www.ncbi.nlm.nih.gov/pubmed/35246212 http://dx.doi.org/10.1186/s13059-022-02640-y |