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Inward Outward Signaling in Ovarian Cancer: Morpho-Phospho-Proteomic Profiling Upon Application of Hypoxia and Shear Stress Characterizes the Adaptive Plasticity of OVCAR-3 and SKOV-3 Cells

With the onset of resistance, ovarian cancer cells display almost unpredictable adaptive potential. This may derive from the tumor genetic ancestry and can be additionally tailored by post translational protein modifications (PTMs). In this study, we took advantage of high-end (phospho)-proteome ana...

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Detalles Bibliográficos
Autores principales: Bileck, Andrea, Bortel, Patricia, Kriz, Michelle, Janker, Lukas, Kiss, Endre, Gerner, Christopher, Del Favero, Giorgia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896345/
https://www.ncbi.nlm.nih.gov/pubmed/35251951
http://dx.doi.org/10.3389/fonc.2021.746411