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Microglia Loss and Astrocyte Activation Cause Dynamic Changes in Hippocampal [(18)F]DPA-714 Uptake in Mouse Models of Depression

Major depression is a serious and chronic mental illness. However, its etiology is poorly understood. Although glial cells have been increasingly implicated in the pathogenesis of depression, the specific role of microglia and astrocytes in stress-induced depression remains unclear. Translocator pro...

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Detalles Bibliográficos
Autores principales: Guo, Jiamei, Qiu, Tian, Wang, Lixia, Shi, Lei, Ai, Ming, Xia, Zhu, Peng, Zhiping, Zheng, Anhai, Li, Xiao, Kuang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896346/
https://www.ncbi.nlm.nih.gov/pubmed/35250485
http://dx.doi.org/10.3389/fncel.2022.802192