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Reconstruction and analysis of a large-scale binary Ras-effector signaling network
BACKGROUND: Ras is a key cellular signaling hub that controls numerous cell fates via multiple downstream effector pathways. While pathways downstream of effectors such as Raf, PI3K and RalGDS are extensively described in the literature, how other effectors signal downstream of Ras is often still en...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896392/ https://www.ncbi.nlm.nih.gov/pubmed/35246154 http://dx.doi.org/10.1186/s12964-022-00823-5 |