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Reconstruction and analysis of a large-scale binary Ras-effector signaling network

BACKGROUND: Ras is a key cellular signaling hub that controls numerous cell fates via multiple downstream effector pathways. While pathways downstream of effectors such as Raf, PI3K and RalGDS are extensively described in the literature, how other effectors signal downstream of Ras is often still en...

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Detalles Bibliográficos
Autores principales: Catozzi, Simona, Ternet, Camille, Gourrege, Alize, Wynne, Kieran, Oliviero, Giorgio, Kiel, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896392/
https://www.ncbi.nlm.nih.gov/pubmed/35246154
http://dx.doi.org/10.1186/s12964-022-00823-5