Accurate and robust inference of microbial growth dynamics from metagenomic sequencing reveals personalized growth rates

Patterns of sequencing coverage along a bacterial genome—summarized by a peak-to-trough ratio (PTR)—have been shown to accurately reflect microbial growth rates, revealing a new facet of microbial dynamics and host–microbe interactions. Here, we introduce Compute PTR (CoPTR): a tool for computing PT...

Descripción completa

Detalles Bibliográficos
Autores principales: Joseph, Tyler A., Chlenski, Philippe, Litman, Aviya, Korem, Tal, Pe'er, Itsik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896461/
https://www.ncbi.nlm.nih.gov/pubmed/34987055
http://dx.doi.org/10.1101/gr.275533.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896461/
https://www.ncbi.nlm.nih.gov/pubmed/34987055
http://dx.doi.org/10.1101/gr.275533.121

Ejemplares similares