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Accurate and robust inference of microbial growth dynamics from metagenomic sequencing reveals personalized growth rates
Patterns of sequencing coverage along a bacterial genome—summarized by a peak-to-trough ratio (PTR)—have been shown to accurately reflect microbial growth rates, revealing a new facet of microbial dynamics and host–microbe interactions. Here, we introduce Compute PTR (CoPTR): a tool for computing PT...
Autores principales: | Joseph, Tyler A., Chlenski, Philippe, Litman, Aviya, Korem, Tal, Pe'er, Itsik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896461/ https://www.ncbi.nlm.nih.gov/pubmed/34987055 http://dx.doi.org/10.1101/gr.275533.121 |
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