Genomic context sensitivity of insulator function

The specificity of interactions between genomic regulatory elements and potential target genes is influenced by the binding of insulator proteins such as CTCF, which can act as potent enhancer blockers when interposed between an enhancer and a promoter in a reporter assay. But not all CTCF sites gen...

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Detalles Bibliográficos
Autores principales: Ribeiro-dos-Santos, André M., Hogan, Megan S., Luther, Raven D., Brosh, Ran, Maurano, Matthew T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896466/
https://www.ncbi.nlm.nih.gov/pubmed/35082140
http://dx.doi.org/10.1101/gr.276449.121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896466/
https://www.ncbi.nlm.nih.gov/pubmed/35082140
http://dx.doi.org/10.1101/gr.276449.121

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