Biophysical Modeling of Dopaminergic Denervation Landscapes in the Striatum Reveals New Therapeutic Strategy

Parkinson’s disease (PD) results from a loss of dopaminergic neurons. What triggers the break-down of neuronal signaling, and how this might be compensated, is not understood. The age of onset, progression and symptoms vary between patients, and our understanding of the clinical variability remains...

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Detalles Bibliográficos
Autores principales: Heltberg, Mathias L., Awada, Hussein N., Lucchetti, Alessandra, Jensen, Mogens H., Dreyer, Jakob K., Rasmussen, Rune N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896595/
https://www.ncbi.nlm.nih.gov/pubmed/35165198
http://dx.doi.org/10.1523/ENEURO.0458-21.2022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896595/
https://www.ncbi.nlm.nih.gov/pubmed/35165198
http://dx.doi.org/10.1523/ENEURO.0458-21.2022

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