Identifying cancer pathway dysregulations using differential causal effects

MOTIVATION: Signaling pathways control cellular behavior. Dysregulated pathways, for example, due to mutations that cause genes and proteins to be expressed abnormally, can lead to diseases, such as cancer. RESULTS: We introduce a novel computational approach, called Differential Causal Effects (dce...

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Detalles Bibliográficos
Autores principales: Jablonski, Kim Philipp, Pirkl, Martin, Ćevid, Domagoj, Bühlmann, Peter, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896597/
https://www.ncbi.nlm.nih.gov/pubmed/34927666
http://dx.doi.org/10.1093/bioinformatics/btab847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896597/
https://www.ncbi.nlm.nih.gov/pubmed/34927666
http://dx.doi.org/10.1093/bioinformatics/btab847

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