Chromosomal imbalances detected via RNA-sequencing in 28 cancers

MOTIVATION: RNA-sequencing (RNA-seq) of tumor tissue is typically only used to measure gene expression. Here, we present a statistical approach that leverages existing RNA-seq data to also detect somatic copy number alterations (SCNAs), a pervasive phenomenon in human cancers, without a need to sequ...

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Detalles Bibliográficos
Autores principales: Ozcan, Zuhal, San Lucas, Francis A, Wong, Justin W, Chang, Kyle, Stopsack, Konrad H, Fowler, Jerry, Jakubek, Yasminka A, Scheet, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896613/
https://www.ncbi.nlm.nih.gov/pubmed/34999743
http://dx.doi.org/10.1093/bioinformatics/btab861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896613/
https://www.ncbi.nlm.nih.gov/pubmed/34999743
http://dx.doi.org/10.1093/bioinformatics/btab861

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