Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testis

The mammalian nuclear hormone receptors LRH1 (NR5A2) and SF1 (NR5A1) are close paralogs that can bind the same DNA motif and play crucial roles in gonadal development and function. Lrh1 is essential for follicle development in the ovary and has been proposed to regulate steroidogenesis in the testis...

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Detalles Bibliográficos
Autores principales: Agrimson, Kellie S., Minkina, Anna, Sadowski, Danielle, Wheeler, Andrew, Murphy, Mark W., Gearhart, Micah D., Bardwell, Vivian J., Zarkower, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896720/
https://www.ncbi.nlm.nih.gov/pubmed/35192609
http://dx.doi.org/10.1371/journal.pgen.1010088

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896720/
https://www.ncbi.nlm.nih.gov/pubmed/35192609
http://dx.doi.org/10.1371/journal.pgen.1010088

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