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Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1
Highly polymorphic interaction of KIR3DL1 and KIR3DS1 with HLA class I ligands modulates the effector functions of natural killer (NK) cells and some T cells. This genetically determined diversity affects severity of infections, immune-mediated diseases, and some cancers, and impacts the course of i...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896733/ https://www.ncbi.nlm.nih.gov/pubmed/35192601 http://dx.doi.org/10.1371/journal.pcbi.1009059 |