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The Complicated Nature of Somatic mtDNA Mutations in Aging
Mitochondria are the main source of energy used to maintain cellular homeostasis. This aspect of mitochondrial biology underlies their putative role in age-associated tissue dysfunction. Proper functioning of the electron transport chain (ETC), which is partially encoded by the extra-nuclear mitocho...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896747/ https://www.ncbi.nlm.nih.gov/pubmed/35252966 http://dx.doi.org/10.3389/fragi.2021.805126 |