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The Complicated Nature of Somatic mtDNA Mutations in Aging

Mitochondria are the main source of energy used to maintain cellular homeostasis. This aspect of mitochondrial biology underlies their putative role in age-associated tissue dysfunction. Proper functioning of the electron transport chain (ETC), which is partially encoded by the extra-nuclear mitocho...

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Detalles Bibliográficos
Autores principales: Sanchez-Contreras, Monica, Kennedy, Scott R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896747/
https://www.ncbi.nlm.nih.gov/pubmed/35252966
http://dx.doi.org/10.3389/fragi.2021.805126