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Cannabidiol Produces Distinct U-Shaped Dose-Response Effects on Cocaine-Induced Conditioned Place Preference and Associated Recruitment of Prelimbic Neurons in Male Rats

BACKGROUND: Cannabidiol (CBD) has received attention for the treatment of substance use disorders. In preclinical models of relapse, CBD attenuates drug seeking across several drugs of abuse, including cocaine. However, in these models CBD has not been consistently effective. This inconsistency in C...

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Detalles Bibliográficos
Autores principales: Nedelescu, Hermina, Wagner, Grant E., De Ness, Genna L., Carroll, Ayla, Kerr, Tony M., Wang, Jingjun, Zhang, Saiwen, Chang, Stephen, Than, Amy H., Emerson, Nora E., Suto, Nobuyoshi, Weiss, Friedbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896771/
https://www.ncbi.nlm.nih.gov/pubmed/35252951
http://dx.doi.org/10.1016/j.bpsgos.2021.06.014