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Protein chain collapse modulation and folding stimulation by GroEL-ES

The collapse of polypeptides is thought important to protein folding, aggregation, intrinsic disorder, and phase separation. However, whether polypeptide collapse is modulated in cells to control protein states is unclear. Here, using integrated protein manipulation and imaging, we show that the cha...

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Detalles Bibliográficos
Autores principales: Naqvi, Mohsin M., Avellaneda, Mario J., Roth, Andrew, Koers, Eline J., Roland, Antoine, Sunderlikova, Vanda, Kramer, Günter, Rye, Hays S., Tans, Sander J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896798/
https://www.ncbi.nlm.nih.gov/pubmed/35245117
http://dx.doi.org/10.1126/sciadv.abl6293