Cargando…

Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia

Microglia interact with neurons to facilitate synapse plasticity; however, signal(s) contributing to microglia activation for synapse elimination in pathology are not fully understood. Here, using in vitro organotypic hippocampal slice cultures and transient middle cerebral artery occlusion (MCAO) i...

Descripción completa

Detalles Bibliográficos
Autores principales: Cramer, Teresa, Gill, Raminder, Thirouin, Zahra S., Vaas, Markus, Sampath, Suchita, Martineau, Fanny, Noya, Sara B., Panzanelli, Patrizia, Sudharshan, Tania J. J., Colameo, David, Chang, Philip K.-Y., Wu, Pei You, Shi, Roy, Barker, Philip A., Brown, Steven A., Paolicelli, Rosa C., Klohs, Jan, McKinney, Rebecca Anne, Tyagarajan, Shiva K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896802/
https://www.ncbi.nlm.nih.gov/pubmed/35245123
http://dx.doi.org/10.1126/sciadv.abj0112