Cross-talk between GABAergic postsynapse and microglia regulate synapse loss after brain ischemia

Microglia interact with neurons to facilitate synapse plasticity; however, signal(s) contributing to microglia activation for synapse elimination in pathology are not fully understood. Here, using in vitro organotypic hippocampal slice cultures and transient middle cerebral artery occlusion (MCAO) i...

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Detalles Bibliográficos
Autores principales: Cramer, Teresa, Gill, Raminder, Thirouin, Zahra S., Vaas, Markus, Sampath, Suchita, Martineau, Fanny, Noya, Sara B., Panzanelli, Patrizia, Sudharshan, Tania J. J., Colameo, David, Chang, Philip K.-Y., Wu, Pei You, Shi, Roy, Barker, Philip A., Brown, Steven A., Paolicelli, Rosa C., Klohs, Jan, McKinney, Rebecca Anne, Tyagarajan, Shiva K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896802/
https://www.ncbi.nlm.nih.gov/pubmed/35245123
http://dx.doi.org/10.1126/sciadv.abj0112

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