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Structural insights into ligand recognition, activation, and signaling of the α(2A) adrenergic receptor

The α(2A) adrenergic receptor (α(2A)AR) is a G protein (heterotrimeric guanine nucleotide–binding protein)–coupled receptor that mediates important physiological functions in response to the endogenous neurotransmitters norepinephrine and epinephrine, as well as numerous chemically distinct drugs. H...

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Detalles Bibliográficos
Autores principales: Xu, Jun, Cao, Sheng, Hübner, Harald, Weikert, Dorothée, Chen, Geng, Lu, Qiuyuan, Yuan, Daopeng, Gmeiner, Peter, Liu, Zheng, Du, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896805/
https://www.ncbi.nlm.nih.gov/pubmed/35245122
http://dx.doi.org/10.1126/sciadv.abj5347