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Structural insights into ligand recognition, activation, and signaling of the α(2A) adrenergic receptor
The α(2A) adrenergic receptor (α(2A)AR) is a G protein (heterotrimeric guanine nucleotide–binding protein)–coupled receptor that mediates important physiological functions in response to the endogenous neurotransmitters norepinephrine and epinephrine, as well as numerous chemically distinct drugs. H...
Autores principales: | Xu, Jun, Cao, Sheng, Hübner, Harald, Weikert, Dorothée, Chen, Geng, Lu, Qiuyuan, Yuan, Daopeng, Gmeiner, Peter, Liu, Zheng, Du, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896805/ https://www.ncbi.nlm.nih.gov/pubmed/35245122 http://dx.doi.org/10.1126/sciadv.abj5347 |
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