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Direct detection of RNA modifications and structure using single-molecule nanopore sequencing

Modifications are present on many classes of RNA, including tRNA, rRNA, and mRNA. These modifications modulate diverse biological processes such as genetic recoding and mRNA export and folding. In addition, modifications can be introduced to RNA molecules using chemical probing strategies that revea...

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Detalles Bibliográficos
Autores principales: Stephenson, William, Razaghi, Roham, Busan, Steven, Weeks, Kevin M., Timp, Winston, Smibert, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8896822/
https://www.ncbi.nlm.nih.gov/pubmed/35252946
http://dx.doi.org/10.1016/j.xgen.2022.100097